Ethylenediamine → 2-[1-(4-Chlorophenyl)propyl]-4,5-dihydro-1H-imidazole

反応式

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH2:11][CH3:12])[C:9]#[N:10])=[CH:4][CH:3]=1.[CH2:13](N)[CH2:14][NH2:15]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]([C:9]2[NH:15][CH2:14][CH2:13][N:10]=2)[CH2:11][CH3:12])=[CH:6][CH:7]=1

参加物

反応物 2

HCID 3301Ethylenediamine

HCID 11435291HCID 11435291、化合物

生成物 1

HCID 589518752-[1-(4-Chlorophenyl)propyl]-4,5-dihydro-1H-imidazole

実験手順

rac-2-[1-(4-Chloro-phenyl)-propyl]-4,5-dihydro-1H-imidazole was prepared from rac-2-(4-chloro-phenyl)butyronitrile and ethylene diamine in analogy to Example 22: colourless powder; MS (ISP): 223.0 ((M+H)+.).

出典と根拠

ORDレコード: ord-68266d1fe95a4654a920ed0533622a06
出典データセット: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07875645B2

反応ノート

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