化工社化工社 化学情報印刷レポート · 研究参考用
Oxalyl chloride → Hexahydro-2,5-methano-pentalene-3a-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | Hexahydro-2,5-methanopentalene-3a(1H)-carboxylic acid | HCID 2733865 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Hexahydro-2,5-methano-pentalene-3a-carbonyl chloride | HCID 13182402 | 99.3% |
反応手順
To a solution of commercially available hexahydro-2,5-methano-pentalene-3a-carboxylic acid (10 g, 0.06 mol) in dichloromethane (200 mL) was added oxalyl chloride (8.7 g, 0.066 mol). The mixture was stirred overnight and then concentrated under reduced pressure to afford the title compound as a colorless oil (11 g, 99%). MS (DCI/NH3) m/z 184 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07875639B2 |
| 出典データセット | uspto-grants-2011_01 |
| ORD ID | ord-82faefc782d147d88966d283fa9acab9 |
| 出典メモ | uspto-grants-2011_01 |