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Benzoic acid, 3-isothiocyanato- → 3-{3-[5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-phenyl]-thioureido}-benzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoic acid, 3-isothiocyanato- | HCID 75046 | — |
| 反応物 | 5-(5,6-dichloro-1H-indol-2-yl)-2-methoxy-phenylamine | HCID 9836191 | — |
| 生成物 | 3-{3-[5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-phenyl]-thioureido}-benzoic acid | HCID 10140976 | — |
反応手順
3-{3-[5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-phenyl]-thioureido}-benzoic acid was prepared from the product of Example 18, Step D, 5-(5,6-dichloro-1H-indol-2-yl)-2-methoxy-phenylamine (0.64 g, 1.72 mmol) and 3-carboxyphenyl isothiocyanate (0.359 g, 2.0 mmol) to give the product as a reddish-tan solid (0.104 g), mp 216-218° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858739B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-fc2f96c8487d4e54b033454790b8d562 |
| 出典メモ | uspto-grants-2005_02 |