化工社化工社 化学情報印刷レポート · 研究参考用
5-(5,6-difluoro1H-indol-2-yl)-2-methoxy-phenylamine → (4-{3-[5-(5,6-Difluoro-1h-indol-2-yl)-2-methoxy-phenyl]-thioureido}-benzyl)-phosphonic acid diethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-(5,6-difluoro1H-indol-2-yl)-2-methoxy-phenylamine | HCID 9943439 | — |
| 反応物 | Diethyl 4-isothiocyanatobenzylphosphonate | HCID 22568434 | — |
| 生成物 | (4-{3-[5-(5,6-Difluoro-1h-indol-2-yl)-2-methoxy-phenyl]-thioureido}-benzyl)-phosphonic acid diethyl ester | HCID 87999803 | — |
反応手順
The product from Example 3, 5-(5,6-difluoro-1H-indol-2-yl)-2-methoxy-phenylamine, (0.137 g, 0.5 mmol) was reacted with the product from Example 23, Step A (0.156 g, 0.54 mmol) according to the procedure for Example 23, Step B to give the product (0.172 g), mp 180-182° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858739B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-fdf2a18672704ebf834b4895c6e25952 |
| 出典メモ | uspto-grants-2005_02 |