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4-Chloro-o-xylene → 2,2'-Dichloro-4,4',5,5'-tetramethylbenzophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Chloro-o-xylene | HCID 32886 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Carbon Disulfide | HCID 6348 | — |
| 生成物 | 2,2'-Dichloro-4,4',5,5'-tetramethylbenzophenone | HCID 15027172 | 67.9% |
反応手順
146 g of AlCl3 are added to a solution of 140 g of 4-chloro-o-xylene and 68 g of oxalyl chloride in 500 ml of CS2 at 0°-5°C. in the course of 2 hours, with stirring. After 20 hours, the mixture is poured onto ice and extracted with 600 ml of CHCl3. The extract is washed with water, dried and evaporated completely. Recrystallisation of the residue from diisopropyl ether gives 103.8 g of 2,2'-dichloro-4,4',5,5'-tetramethylbenzophenone (D). Melting point: 148°-149° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04698295 |
| 出典データセット | uspto-grants-1987_10 |
| ORD ID | ord-a1700d5b417a47799cf30df7de44a2e5 |
| 出典メモ | uspto-grants-1987_10 |