Hydrochloric Acid → HCID 54158343、化合物
反応式
C([O:3][C:4]([CH:6]=[CH:7][C:8]1[N:9]([C:18]2[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][C:19]=2[CH3:25])[CH:10]=[C:11]([C:15](=[O:17])[CH:16]=1)[C:12]([OH:14])=[O:13])=[O:5])C.Cl>C(OCC)C>[C:4]([CH:6]=[CH:7][C:8]1[N:9]([C:18]2[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][C:19]=2[CH3:25])[CH:10]=[C:11]([C:15](=[O:17])[CH:16]=1)[C:12]([OH:14])=[O:13])([OH:5])=[O:3]参加物
4
実験手順
To 0.09 g of 6-(2-ethoxycarbonylethenyl)-1-(4-hydroxy-2-methylphenyl)-4-oxo-1,4-dihydronicotinic acid was added 3 ml of 6N hydrochloric acid, and they were reacted at 100° C. for 1.5 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure, and to the crystals thus formed were added 3 ml of diethyl ether, and the resulting mixture was filtered to obtain 0.08 g of 6-(2-carboxyethenyl)-1-(4-hydroxy-2-methylphenyl)-4-oxo-1,4-dihydronicotinic acid having a melting point of 280° C. or more.