Formic Acid → N-[4-(pyrazol-3-yl)-phenyl]-formamide

HRID 255898ノート

反応式

HRID 255898 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:12]=[CH:11][NH:10][N:9]=2)=[CH:4][CH:3]=1.[CH:13](O)=[O:14]>>[NH:10]1[CH:11]=[CH:12][C:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][CH:13]=[O:14])=[CH:7][CH:6]=2)=[N:9]1

参加物

3

反応物 2

HCID 284Formic AcidHCID 178507410HCID 178507410、化合物

生成物 1

HCID 178521884N-[4-(pyrazol-3-yl)-phenyl]-formamide

実験手順

A solution of 3-(4-aminophenyl)-1-H-pyrazole (10 g) in formic acid (100 ml) was refluxed for 4 hours and evaporated to dryness. The residue was dissolved in water, and the solution was filtered through charcoal. The filtrate was made basic to give 9.5 g of N-[4-(pyrazol-3-yl)-phenyl]-formamide; M.p. 139°-141° C.

後処理

  1. customevaporated to dryness
  2. dissolutionThe residue was dissolved in water
  3. filtrationthe solution was filtered through charcoal

出典と根拠

ORDレコード
ord-b2b7a73cc6ec48419cbf78d69bc77c45
出典データセット
uspto-grants-1987_10
特許番号
US04699915

反応ノート

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