Butanedione → Ethyl 2-(1-hydroxy-1-methyl-2-oxopropyl)-2-methylundecanoate

HRID 256133

反応式

HRID 256133 の反応式
[CH3:1][CH:2]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH3:17][C:18](=[O:22])[C:19](=[O:21])[CH3:20]>CCCCCC>[OH:21][C:19]([C:2]([CH3:1])([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:3]([O:5][CH2:6][CH3:7])=[O:4])([CH3:20])[C:18](=[O:22])[CH3:17]

参加物

4

反応物 2

HCID 650ButanedioneHCID 14532384HCID 14532384、化合物

生成物 1

HCID 20164024Ethyl 2-(1-hydroxy-1-methyl-2-oxopropyl)-2-methylundecanoate収率 59%

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

実験手順

The reaction of ethyl 2-methylundecanoate (11.4 g, 0.05 mole) with 2,3-butanedione (4.73 g, 0.055 mole) is conducted in the manner described in Example I, and 16.6 g of a crude oil is obtained. The crude oil product is subjected to high pressure liquid chromatography on silica gel using 5% ethyl acetate in hexane as the eluant, yielding a pure product (9.2 g, 59%), b.p. 100° C. (Kugelrohr air bath temperature) at 0.01 mm Hg.

後処理

  1. custom16.6 g of a crude oil is obtained

出典と根拠

ORDレコード
ord-4c6ff510021f439aab53270d16294508
出典データセット
uspto-grants-1987_10
特許番号
US04701282

関連ノート

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