Stearic Acid → Azulenesulfonic acid
反応式
[C:1]1([S:11]([O-:14])(=[O:13])=[O:12])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1.[Na+].C(O)(=O)CCCCCCCCCCCCCCCCC>>[C:1]1([S:11]([OH:14])(=[O:12])=[O:13])[C:10]2[C:4]([CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)=[CH:3][CH:2]=1参加物
3
反応条件
- 温度
- 80 °C
実験手順
Sodium azulenesulfonate (12 g), 186 g of hydroxypropylcellulose-M and 282 g of stearic acid were granulated by the same way as in Example 5. Each 160 mg of it was filled in a capsule No. 3. The capsules were placed in a fluidized bed granulator-drier, fluidized by heating with air (intake temperature: 80° C.) for 15 minutes, the heater was turned off and allowed to cool with air of the room temperature to give capsules each containing 4 mg of azulenesulfonic acid.
後処理
- additionEach 160 mg of it was filled in a capsule No
- temperatureto cool with air of the room temperature
出典と根拠
- ORDレコード
- ord-d8bbaed987ed479a8c9abd44a4e1fad7
- 出典データセット
- uspto-grants-1987_10
- 特許番号
- US04702918
反応ノート
読み込み中…