Phosphorus oxychloride → 7-[2-(2-Formamido-5-bromothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid

反応式

P(Cl)(Cl)(Cl)=O.[CH:6]([NH:8][C:9]1[S:10][C:11]([Br:21])=[C:12]([C:14](=[N:18][O:19][CH3:20])[C:15]([OH:17])=O)[N:13]=1)=[O:7].[NH2:22][CH:23]1[C:41](=[O:42])[N:25]2[C:26]([C:38]([OH:40])=[O:39])=[C:27]([CH2:30][S:31][C:32]3[S:33][C:34]([CH3:37])=[N:35][N:36]=3)[CH2:28][S:29][C@H:24]12.C[Si](CC(N)=O)(C)C>C(OCC)(=O)C.O.CN(C)C=O>[CH:6]([NH:8][C:9]1[S:10][C:11]([Br:21])=[C:12]([C:14](=[N:18][O:19][CH3:20])[C:15]([NH:22][CH:23]2[C:41](=[O:42])[N:25]3[C:26]([C:38]([OH:40])=[O:39])=[C:27]([CH2:30][S:31][C:32]4[S:33][C:34]([CH3:37])=[N:35][N:36]=4)[CH2:28][S:29][C@H:24]23)=[O:17])[N:13]=1)=[O:7]