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Monobasic potassium phosphate → Ribavirin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Monobasic potassium phosphate | HCID 516951 | — |
| 反応物 | HCID 178418936 | HCID 178418936 | — |
| 反応物 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxypurin-9-yl)oxolane-3,4-diol | HCID 178521066 | — |
| 生成物 | Ribavirin | HCID 37542 | — |
反応手順
By using a substrate solution (pH 6.0) containing 40 mM triazole as the base donor, 60 mM inosine as the saccharide residue donor and 40 mM potassium dihydrogenphosphate, reactions were carried out in the same manner as in Example 1 at respective reaction temperature (40° to 70° C.) for 24 hours to produce ribavirin. The results are shown in Table 8.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05258301 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-ad34d5e319f442798901411e2fa06cde |
| 出典メモ | uspto-grants-1993_11 |