Methanol → 3-Methoxy-3-oxo-2-phenylpropanoic acid

HRID 256575ノート

反応式

HRID 256575 の反応式
[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.B(F)(F)F.[CH3:18]COCC.CO>>[C:1]1([CH:7]([C:11]([OH:13])=[O:12])[C:8]([O:10][CH3:18])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 887MethanolHCID 8000Boron trifluoride etherateHCID 75791Phenylmalonic acid

生成物 1

HCID 28177753-Methoxy-3-oxo-2-phenylpropanoic acid

実験手順

A mixture of phenylmalonic acid (3.6 g, 0.02 mol), boron trifluoride etherate (2.4 mL, 0.02 mol) and 0.8 mL of anhydrous methanol (0.02 mol) was refluxed and stirred for 24 hours. After cooling to room temperature, the reaction mixture was filtered and 20 mL of water was added.

後処理

  1. temperaturewas refluxed
  2. filtrationthe reaction mixture was filtered
  3. addition20 mL of water was added

出典と根拠

ORDレコード
ord-351c1ca7330d49efafb2ef3ae97aebf1
出典データセット
uspto-grants-1993_11
特許番号
US05258388

反応ノート

読み込み中…