Toluene → HCID 11030613、化合物

HRID 256734ノート

反応式

HRID 256734 の反応式
[Cl:1][C:2]([CH2:4]Cl)=[CH2:3].[CH2:6]([OH:13])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C1(C)C=CC=CC=1>[Zn].O>[Cl:1][C:2](=[CH2:3])[CH2:4][CH:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[OH:13]

参加物

6

反応物 3

HCID 1140TolueneHCID 65652,3-DichloropropeneHCID 8129Heptanol

生成物 1

HCID 11030613HCID 11030613、化合物収率 94.1%

試薬・触媒・溶媒 2

HCID 23994Zinc触媒2 回HCID 962Water溶媒

実験手順

58.30 Grams of 2,3-dichloro-1-propene were added dropwise to a mixture of 30.00 g of heptanol, 90 g of toluene, 120 g of water and 34.35 g of zinc powder at 45° C., and then, the resultant mixture was allowed to react at the same temperature for 10 hours. After the reaction finished, zinc-derived insolubles were filtered off, and the resultant filtrate was subjected to separation. The organic phase was washed with a 7% sodium carbonate aqueous solution and then dried over sodium sulfate. The desiccant was filtered off, and then the toluene was distilled off under reduced pressure to give 47.14 g of 2-chloroallyl-n-hexyl-carbinol. The results were as follows.

後処理

  1. customto react at the same temperature for 10 hours
  2. filtrationwere filtered off
  3. customthe resultant filtrate was subjected to separation
  4. washThe organic phase was washed with a 7% sodium carbonate aqueous solution
  5. dry with materialdried over sodium sulfate
  6. filtrationThe desiccant was filtered off
  7. distillationthe toluene was distilled off under reduced pressure

出典と根拠

ORDレコード
ord-c42d386a62224af0bef444e5bc769caf
出典データセット
uspto-grants-1993_11
特許番号
US05258529

反応ノート

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