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1-(4-methoxyphenyl)-N-methylmethanamine → 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-methoxyphenyl)-N-methylmethanamine | HCID 485407 | — |
| 反応物 | 1-(4-Nitrophenyl)piperidin-4-one | HCID 3842562 | — |
| 生成物 | 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine | HCID 19784354 | 72.4% |
反応手順
3.0 g (13.6 mmol) of 1-(4-nitrophenyl)-4-piperidone and 2.0 g (13.6 mmol) of N-(4-methoxybenzyl)-N-methylamine were reacted in a similar manner to Example 1. 3.5 g of 4-(N-(4-methoxybenzyl)-N-methylamino)-1-(4-nitrophenyl)piperidine were obtained. Melting point 144°-145° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05260318 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-7f9b91675af14320a1c9c71b9336bdf2 |
| 出典メモ | uspto-grants-1993_11 |