n-Methyl-3-nitropyridin-4-amine → 4-N-methylpyridine-3,4-diamine

HRID 257415

反応式

HRID 257415 の反応式
[N+:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11])([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[NH:10][CH3:11]

参加物

4

反応物 1

HCID 556016n-Methyl-3-nitropyridin-4-amine

生成物 1

HCID 9104124-N-methylpyridine-3,4-diamine収率 80%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 702Ethanol溶媒

実験手順

150 mg of platinum oxide was added to 10 ml of a solution of 3-nitro-4-methylaminopyridine (1.5 g) in ethanol. The mixture was stirred under a hydrogen atmosphere at room temperature for 7.5 hours. Platinum oxide was removed by filtration, and the filtrate was concentrated. Thus, 962 mg (yield: 80%) of the intended product was obtained as brown crude crystals.

後処理

  1. customPlatinum oxide was removed by filtration
  2. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-484ff4d8aee143319be9cb8ee8336d05
出典データセット
uspto-grants-1993_11
特許番号
US05262415

関連ノート

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