Methylamine → N-methyl-5-nitropyridin-2-amine
反応式
[N+:1]([C:4]1[CH:5]=[N:6][C:7](Cl)=[CH:8][CH:9]=1)([O-:3])=[O:2].[CH3:11][NH2:12]>C(O)C>[N+:1]([C:4]1[CH:5]=[N:6][C:7]([NH:12][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2]参加物
4
実験手順
3-Nitro-6-chloropyridine (5 g, 31.5 mmol) was added to 10 ml of a 30% solution of methylamine in ethanol, followed by reaction at room temperature for 5 minutes. Then, recrystallization from chloroform-hexane gave 4.92 g of the intended product as yellow crude crystals.
後処理
- customfollowed by reaction at room temperature for 5 minutes
- customThen, recrystallization from chloroform-hexane
出典と根拠
- ORDレコード
- ord-44b7ea052e4c4c96a317178936f110bd
- 出典データセット
- uspto-grants-1993_11
- 特許番号
- US05262415
反応ノート
読み込み中…