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Allyl Alcohol → [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Allyl Alcohol | HCID 7858 | — |
| 反応物 | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| 反応物 | Dihydroquinoline-based ligand, 15 | HCID 10314903 | — |
| 反応物 | 4-(Bromomethyl)-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline | HCID 22566535 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | [6-(2-Methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinolin-4-ylmethyl]phenylamine | HCID 10406857 | — |
反応手順
4-Allyloxymethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline 40 mg of 4-bromomethyl-6-(2-methoxyphenyl)-2,2-dimethyl-1,2-dihydroquinoline, 44 μL of allyl alcohol, and 4 mL of 1 M solution of sodium bis(trimethylsilyl)amide in THF reacted to give 4.5 mg of the title compound as a foam.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858627B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-327afb34ff494ccc98e407e845ba3144 |
| 出典メモ | uspto-grants-2005_02 |