化工社化工社 化学情報印刷レポート · 研究参考用
Triisopropyl borate → Boronic acid, B-(2-(((1,1-dimethylethyl)amino)sulfonyl)phenyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triisopropyl borate | HCID 21531 | — |
| 反応物 | N-(1,1-Dimethylethyl)benzenesulfonamide | HCID 314059 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 生成物 | Boronic acid, B-(2-(((1,1-dimethylethyl)amino)sulfonyl)phenyl)- | HCID 4997616 | — |
反応手順
By the method described in Example 10, Step B, N-t-butylbenzenesulfonamide [G. Lombardino, J. Org. Chem., 36, 1843 (1971)] was deprotonated with n-butyllithium, and the resulting dianion was reacted with triisopropyl borate and worked up with acid to give the title compound, which was used directly in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05262412 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-45a3114f918c4e9b96cbd287d3a35cb3 |
| 出典メモ | uspto-grants-1993_11 |