化工社化工社 化学情報印刷レポート · 研究参考用
4-Bromobutyryl chloride → 5-(4-Diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromobutyryl chloride | HCID 70225 | — |
| 反応物 | 5,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one | HCID 201327 | — |
| 反応物 | 5-(4-bromobutyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one | HCID 10737151 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 5-(4-Diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one | HCID 15115499 | — |
反応手順
The 5-(4-bromobutyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one, starting material, was synthesized similarly to the starting material described in Example 1, from 5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one and 4-bromobutyryl chloride. The yield is 74.3% of the theoretical yield and the melting point is 159°-161° C. (toluene).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05264432 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-d7b8681b86894f4c8a6680f86fef89c1 |
| 出典メモ | uspto-grants-1993_11 |