化工社化工社 化学情報印刷レポート · 研究参考用
2-Phenylethanethiol → 6-Biphenyl-2-yl-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Phenylethanethiol | HCID 78126 | — |
| 反応物 | Biphenyl-2-boronic acid | HCID 4589187 | — |
| 反応物 | Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester | HCID 20760320 | — |
| 生成物 | 6-Biphenyl-2-yl-2,2-dimethyl-4-phenethylsulfanylmethyl-1,2-dihydroquinoline | HCID 10367062 | — |
反応手順
Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester was coupled with 2-biphenylboronic acid. Bromination and coupling reaction with 2-phenylethanethiol gave 57 mg of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858627B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-c19277094bb64775bc862ab3379cb694 |
| 出典メモ | uspto-grants-2005_02 |