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2-Phenylethanethiol → 2,2-Dimethyl-6-(2-methylsulfanylphenyl)-4-phenethylsulfanylmethyl-1,2-dihydroquinoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Phenylethanethiol | HCID 78126 | — |
| 反応物 | 2-(Methylthio)benzeneboronic acid | HCID 2773543 | — |
| 反応物 | Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester | HCID 20760320 | — |
| 生成物 | 2,2-Dimethyl-6-(2-methylsulfanylphenyl)-4-phenethylsulfanylmethyl-1,2-dihydroquinoline | HCID 10455467 | — |
反応手順
Trifluoromethanesulfonic acid 2,2,4-trimethyl-1,2-dihydroquinolin-6-yl ester was coupled with 2-(methylthio)phenylboronic acid. Bromination and coupling reaction with 2-phenylethanethiol gave 59 mg of the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06858627B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-7038e07fd43c47049bcde43c3da206c3 |
| 出典メモ | uspto-grants-2005_02 |