Acetone → 6-(2-Chlorobenzoyl)-5-(2-nitroethenylamino)indan

HRID 258036ノート

反応式

HRID 258036 の反応式
O1[CH2:6][CH2:5][N:4]([CH:7]=[CH:8][N+:9]([O-:11])=[O:10])CC1.NC1C=[C:15]2[C:19](=[CH:20][C:21]=1[C:22](=[O:30])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[Cl:29])[CH2:18][CH2:17][CH2:16]2.Cl.CC(C)=O>O>[Cl:29][C:24]1[CH:25]=[CH:26][CH:27]=[CH:28][C:23]=1[C:22]([C:21]1[CH:20]=[C:19]2[C:18]([CH2:17][CH2:16][CH2:15]2)=[CH:6][C:5]=1[NH:4][CH:7]=[CH:8][N+:9]([O-:11])=[O:10])=[O:30]

参加物

6

反応物 4

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 683970Morpholine, 4-(2-nitroethenyl)-HCID 199365705-Amino-6-(2-chlorobenzoyl)indan

生成物 1

HCID 677827716-(2-Chlorobenzoyl)-5-(2-nitroethenylamino)indan収率 95.2%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-Morpholino-2-nitroethene (3.93 g) was added to a mixture of 5-amino-6-(2-chlorobenzoyl)indan (4.50 g), 6N HCl (15 ml) and acetone (45 ml) and the whole mixture was stirred at room temperature for one hour. To this reaction mixture was added water to give crystals of 6-(2-chlorobenzoyl)-5-(2-nitroethenylamino)indan (5.40 g, 95.2%). Recrystallization from ethanol gave yellow needles, mp. 225°-226° C.

出典と根拠

ORDレコード
ord-abb5a35b811545fb94ed193b1144da2e
出典データセット
uspto-grants-1993_11
特許番号
US05264454

反応ノート

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