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Isobutyronitrile → 2,9-Dicyano-2,9-dimethyldecane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isobutyronitrile | HCID 6559 | — |
| 反応物 | Diisopropylamine | HCID 7912 | — |
| 反応物 | 1,6-Dibromohexane | HCID 12368 | — |
| 反応物 | 2-Cyano-2-methyleicosane | HCID 19781207 | — |
| 反応物 | Butyllithium | HCID 178418339 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 2,9-Dicyano-2,9-dimethyldecane | HCID 19781205 | — |
反応手順
By the procedure used to prepare the compound of Example 2, the title compound is prepared from 24 mL of a 2.5M n-butyllithium solution in hexanes, 6.07 g of diisopropylamine, 5.5 mL of isobutyronitrile, 7.32 g of 1,6-dibromohexane, and 120 mL of tetrahydrofuran. The IR and 1H NMR spectra of the white solid (7.7 g) obtained were consistent with structure of the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05266726 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-0ebf857b948a47fc993f27b4d2982bd9 |
| 出典メモ | uspto-grants-1993_11 |