Diethyl Ether → Ethyl 2-(acetylthiomethyl)butanoate

HRID 258484

反応式

HRID 258484 の反応式
[CH2:1]([C:3](=[CH2:9])[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].[S:10]1C=CC=C1CC(O)=O.[CH3:19][CH2:20][O:21]CC>>[C:20]([S:10][CH2:9][CH:3]([CH2:1][CH3:2])[C:4]([O:6][CH2:7][CH3:8])=[O:5])(=[O:21])[CH3:19]

参加物

4

反応物 3

HCID 3283Diethyl EtherHCID 159702-Thiopheneacetic acidHCID 291416Ethyl 2-methylidenebutanoate

生成物 1

HCID 15025921Ethyl 2-(acetylthiomethyl)butanoate

反応条件

温度
65 °C

実験手順

Ethyl 2-ethylpropenoate (5 g, 39 mmol) was diluted with 5.6 mL (78 mmol) of thiolacetic acid and stirred at 65° C. for 36 h. The mixture was then diluted with ether, washed with water and the organic phase was dried with Na2SO4. Evaporation to dryness yielded the title material as an orange oil which was used as such for the next step.

後処理

  1. washwashed with water
  2. dry with materialthe organic phase was dried with Na2SO4
  3. customEvaporation to dryness

出典と根拠

ORDレコード
ord-ddda9115889046ae9570164ebc99bd6f
出典データセット
uspto-grants-1993_11
特許番号
US05266568

関連ノート

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