化工社化工社 化学情報印刷レポート · 研究参考用
p-Chloro-o-toluidine hydrochloride → Formamide, N-(2-methylphenyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Chloro-o-toluidine hydrochloride | HCID 18487 | — |
| 反応物 | N-(4-Chloro-2-methylphenyl)formamide | HCID 30815 | — |
| 反応物 | 2-Amino-6-methylbenzaldehyde | HCID 23046538 | — |
| 反応物 | 6-Chloro-o-toluidine hydrochloride | HCID 68119497 | — |
| 生成物 | Formamide, N-(2-methylphenyl)- | HCID 7202 | — |
反応手順
An improved process for the production of 2-amino-chlorotoluene hydrochloride comprising chlorination of 2-formyl-amino-toluene, splitting off the formyl group of the 2-formyl-amino-chlorotoluenes and isolation of crystalline 2-amino-5-chlorotoluene hydrochloride is disclosed, in which process the 2-formylamino-5-chlorotoluene formed by chlorination of 2-formylamino-toluene in an inert solvent is reacted with methanol to form 2-amino-5-chlorotoluene and methyl formate, and the 2-amino-5-chlorotoluene is isolated as hydrochloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04034043 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-b80a11e7fe074d66bb599d45cf0c834b |
| 出典メモ | uspto-grants-1977_07 |