化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl benzoylacetate → 3-Benzoyl-5,7-dimethoxy-2H-1-benzopyran-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl benzoylacetate | HCID 7170 | — |
| 反応物 | 4,6-Dimethoxysalicylaldehyde | HCID 69725 | — |
| 触媒 | Piperidine | HCID 8082 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 3-Benzoyl-5,7-dimethoxy-2H-1-benzopyran-2-one | HCID 12777075 | — |
反応手順
A mixture of 18.2 g 4,6-dimethoxysalicylaldehyde, 20.0 g ethyl benzoylacetate, 20 ml acetonitrile and 30 drops piperidine was heated gently on a hot plate for 45 minutes. After cooling the product was collected and recrystallized twice from acetonitrile and once from benzene containing a small amount of acetonitrile. m.p. 178° C.-179° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147552 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-ebb76a967e5e457da245dada4c59a35b |
| 出典メモ | uspto-grants-1979_04 |