化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl Acetoacetate → 3-Acetyl-7-methoxycoumarin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Acetoacetate | HCID 8868 | — |
| 反応物 | 2-Hydroxy-4-Methoxybenzaldehyde | HCID 69600 | — |
| 触媒 | Piperidine | HCID 8082 | — |
| 生成物 | 3-Acetyl-7-methoxycoumarin | HCID 2054475 | — |
反応手順
A mixture of 15.2 g 2-hydroxy-4-methoxybenzaldehyde and 13.5 g ethyl acetoacetate was warmed on a hot plate until solution was attained. Thirty drops of piperidine were added and the reaction mixture continued to be heated gently. After several minutes the reaction mixture solidified. After cooling, the product was recrystallized from a mixture of alcohol and acetonitrile. Yield 20 g.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147552 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-0dc7f5bd4b6b41e582a9b7b4128509d7 |
| 出典メモ | uspto-grants-1979_04 |