1-Hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene → 1-Hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene

HRID 25890ノート

反応式

HRID 25890 の反応式
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][CH2:6][C:5]([CH3:10])([CH3:9])[C:4]=1[CH3:11]>C(O)C.[Ni]>[OH:1][CH2:2][C:3]1[CH:4]([CH3:11])[C:5]([CH3:10])([CH3:9])[CH2:6][CH2:7][CH:8]=1

参加物

4

反応物 1

HCID 205694331-Hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene

生成物 1

HCID 213256291-Hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene収率 91.6%

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 702Ethanol溶媒

実験手順

30.4 g of 1-hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene were hydrogenated at 10°-12° in the presence of 1g of Raney-nickel in 300 ml of ethanol. 3.95 l of hydrogen were then absorbed within 2.5 h. A filtration followed by evaporation and distillation gave 28.2 g of 1-hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene. nD = 1.4862, d20 = 9.9447

後処理

  1. custom3.95 l of hydrogen were then absorbed within 2.5 h
  2. filtrationA filtration
  3. customfollowed by evaporation and distillation

出典と根拠

ORDレコード
ord-91f4dcac6ae64b8d866b0c8e8c0a5112
出典データセット
uspto-grants-1979_04
特許番号
US04147672

反応ノート

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