Benzaldehyde → 1-Phenyl-1,4-pentanedione

HRID 258944

反応式

HRID 258944 の反応式
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9]([C:11]([CH3:13])=[O:12])=[CH2:10].N(CCO)(CCO)CCO>CN(C)C=O>[C:2]1([C:1](=[O:8])[CH2:10][CH2:9][C:11](=[O:12])[CH3:13])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

5

反応物 3

HCID 240BenzaldehydeHCID 6570Methyl vinyl ketoneHCID 7618Triethanolamine

生成物 1

HCID 1363711-Phenyl-1,4-pentanedione

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

Following the description in Example 1, 5.1 g (approx. 0.02 mol) of Cat. 3, 21.2 g (0.2 mol) of distilled benzaldehyde, 350 ml of dimethylformamide and 14 g (0.2 mol) of stabilized methyl vinyl ketone are introduced into a 500 ml three-necked flask. After displacing the air by pure nitrogen, the mixture is brought to a temperature of 80° C and 14.9 g (0.1 mol) of triethanolamine are added. The mixture is then stirred for 15 hours at the same temperature. Working up takes place as in Example 11 except that the mixture is filtered after having been taken up in chloroform. 1-Phenyl-pentane-1,4-dione is obtained.

後処理

  1. additionare added
  2. filtrationis filtered

出典と根拠

ORDレコード
ord-34a209383a6b4391bde49ecd8a0da465
出典データセット
uspto-grants-1977_07
特許番号
US04035395

関連ノート

読み込み中…