化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Dimethylmalonyl Dichloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Sulfur Dioxide | HCID 1119 | — |
| 反応物 | Dimethylmalonic acid | HCID 11686 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | Dimethylmalonyl Dichloride | HCID 4523180 | — |
反応手順
To a 500 ml. one-necked flask equipped with reflux condenser with drying tube, is added 50 grams (0.38 mole) dimethylmalonic acid (Aldrich Chemical Co.) and 300 ml. thionyl chloride. The mixture is heated to reflux for about 1 hour during which time the dimethylmalonic acid is dissolved and hydrogen chloride and sulfur dioxide are evolved. The unreacted thionyl chloride is removed by distillation under reduced pressure. The residue is recrystallized twice from cyclohexane to yield a white solid, M.P. 186°-187° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04035437 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-38581de9b1114be4935b945dafac826a |
| 出典メモ | uspto-grants-1977_07 |