Phosphoric Acid → Maltol

反応式

Br[C:2]1[C:3](=[O:10])[CH:4]([CH3:9])[O:5][CH:6](O)[CH:7]=1.P(=O)(O)(O)[OH:12]>>[CH3:9][C:4]1[O:5][CH:6]=[CH:7][C:2](=[O:12])[C:3]=1[OH:10]

参加物

反応物 2

HCID 1004Phosphoric Acid

HCID 204685984-Bromo-6-hydroxy-2-methyl-2H-pyran-3(6H)-one

生成物 1

HCID 8369Maltol収率 34%

実験手順

A solution of 4-bromo-6-hydroxy-2-methyl-2H-pyran-3(6H)-one (0.0025 mole) in 20 ml of 35% phosphoric acid was refluxed for about 5 hours. Maltol (34%) was isolated by the method of Example 1.

出典と根拠

ORDレコード: ord-789a08dd972b4ebabbf1cd68f5b9406e
出典データセット: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04147705

反応ノート

読み込み中…