Dimethylamine → 2-hydroxymethyl-5-nitro-N,N-dimethylbenzamide

HRID 259100

反応式

HRID 259100 の反応式
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][O:9][C:10]2=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:14][NH:15][CH3:16]>C(O)C>[OH:9][CH2:8][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:13][C:12]=1[C:10]([N:15]([CH3:16])[CH3:14])=[O:11]

参加物

4

反応物 2

HCID 674DimethylamineHCID 2235846-Nitrophthalide

生成物 1

HCID 214230322-hydroxymethyl-5-nitro-N,N-dimethylbenzamide

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

To a stirred solution of 6-nitrophthalide (2 g.) in ethanol (120 ml.) at room temperature was added dimethylamine (in ethanol 33.3% solution: 50 ml.). After stirring for 5 hours the solvent was evaporated off. The resulting gum was dissolved in ethyl acetate. On addition of petrol 60° - 80° a white solid crystallised out.

後処理

  1. customwas evaporated off
  2. dissolutionThe resulting gum was dissolved in ethyl acetate
  3. additionOn addition of petrol 60° - 80° a white solid
  4. customcrystallised out

出典と根拠

ORDレコード
ord-629edec6f3314e72a6d0267038f5bf6e
出典データセット
uspto-grants-1977_07
特許番号
US04036829

関連ノート

読み込み中…