Hydrochloric Acid → HCID 20356988、化合物

反応式

[CH2:1]1[O:13][C:12]2[CH:11]=[C:10]3[C:5]([C:6](=[O:24])[C:7]([C:19]([O:21]CC)=[O:20])=[CH:8][N:9]3[CH2:14][C:15]([F:18])([F:17])[F:16])=[CH:4][C:3]=2[O:2]1.Cl>>[CH2:1]1[O:13][C:12]2[CH:11]=[C:10]3[C:5]([C:6](=[O:24])[C:7]([C:19]([OH:21])=[O:20])=[CH:8][N:9]3[CH2:14][C:15]([F:18])([F:17])[F:16])=[CH:4][C:3]=2[O:2]1

参加物

反応物 2

HCID 313Hydrochloric Acid

HCID 86734955HCID 86734955、化合物

生成物 1

HCID 20356988HCID 20356988、化合物

実験手順

A mixture of 1 g. of the ethyl ester obtained from Example 3 and 40 ml. of 6N. hydrochloric acid was heated under reflux for 11/2 hours. The mixture was cooled and the solid product was collected by filtration and washed with water and dried under reduced pressure, m.p. 323°-5° C. (dec.).

後処理

additionA mixture of 1 g
temperatureunder reflux for 11/2 hours
temperatureThe mixture was cooled
filtrationthe solid product was collected by filtration
washwashed with water
customdried under reduced pressure, m.p. 323°-5° C. (dec.)

出典と根拠

ORDレコード: ord-e256dc4aa1df43379ff3131c713ff48c
出典データセット: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04036962

反応ノート

読み込み中…

参加物