Sodium hydroxide methanol → Sodium 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylate

HRID 259248

反応式

HRID 259248 の反応式
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=2)=[O:12])=[CH:7][N:6]=1)=[O:4].CO.[OH-].[Na+:24]>>[Cl:20][C:16]1[CH:15]=[C:14]([CH:19]=[CH:18][CH:17]=1)[CH2:13][S:11]([C:8]1[CH:9]=[CH:10][C:5]([C:3]([O-:4])=[O:2])=[N:6][CH:7]=1)=[O:12].[Na+:24]

参加物

3

反応物 2

HCID 23721981Sodium hydroxide methanolHCID 537728025-(m-Chlorobenzylsulfinyl)-2-pyridinecarboxylic acid methyl ester

生成物 1

HCID 23712206Sodium 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylate

実験手順

To the stirred mixture of 9 g of 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylic acid methyl ester and 40 ml of N aqueous sodium hydroxide methanol is added until dissolution occurs. The solution is heated at the steam bath for 10 minutes and stirred overnight at room temperature. It is evaporated, the residue taken up in the minimum amount of hot water, the solution filtered, the filtrate cooled and the precipitate formed collected, to yield the sodium 5-(m-chlorobenzylsulfinyl)-2-pyridinecarboxylate.

後処理

  1. additionis added until dissolution
  2. temperatureThe solution is heated at the steam bath for 10 minutes
  3. customIt is evaporated
  4. filtrationthe solution filtered
  5. temperaturethe filtrate cooled
  6. customthe precipitate formed
  7. customcollected

出典と根拠

ORDレコード
ord-8193c3a539c04da494a76533be71fa8b
出典データセット
uspto-grants-1977_07
特許番号
US04036965

関連ノート

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