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Tetrahydrofuran → 1-(5-Bromofurylideneamino)-2-oxo-imidazolidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 5-Bromofuran-2-carbaldehyde | HCID 600328 | — |
| 反応物 | 1-Amino-2-imidazolidinone hydrochloride | HCID 19261678 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1-(5-Bromofurylideneamino)-2-oxo-imidazolidine | HCID 70571814 | — |
反応手順
33.5 pts. by wt. of 2-bromofuran-5-aldehyde, dissolved in 100 pts. by vol. of THF, are added to a solution of 1-amino-2-oxo-imidazolidine hydrochloride in 350 pts. by vol. of water, which has been adjusted to pH 5 with sodium hydroxide solution, and the mixture is stirred overnight. The precipitate is filtered off, washed with water and recrystallised from methanol. 30.0 pts. by wt. of 1-(5-bromofurylideneamino)-2-oxo-imidazolidine of dec. pt. 153°-158° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147693 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-5fe05e38426c4bce8f418d26222a5c9f |
| 出典メモ | uspto-grants-1979_04 |