5-Methyl-1,2-oxazole-3-carbaldehyde → 1-{[(5-Methyl-1,2-oxazol-3-yl)methylidene]amino}imidazolidin-2-one
反応式
[CH3:1][C:2]1[O:6][N:5]=[C:4]([CH:7]=O)[CH:3]=1.Cl.[NH2:10][N:11]1[CH2:15][CH2:14][NH:13][C:12]1=[O:16]>O>[CH3:1][C:2]1[O:6][N:5]=[C:4]([CH:7]=[N:10][N:11]2[CH2:15][CH2:14][NH:13][C:12]2=[O:16])[CH:3]=1参加物
4
実験手順
14.0 pts. by wt. of 5-methyl-3-formyl-isoxazole are reacted with 25.6 pts. by wt. of 1-amino-2-oxo-imidazolidine hydrochloride in 100 pts. by vol. of water as in Example 25.1. After 90 minutes, the precipitate is filtered off, washed with water, dried and recrystallised from absolute acetonitrile. 12.5 pts. by wt. of 1-(5-methyl-isoxazol-3-yl-methyleneamino)-2-oxo-imidazolidine of melting point 195°-7° C. are obtained.
後処理
- filtrationthe precipitate is filtered off
- washwashed with water
- customdried
- customrecrystallised from absolute acetonitrile
出典と根拠
- ORDレコード
- ord-139d17def34245298714a3e2a6ba331f
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147693
反応ノート
読み込み中…