関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitrobenzene | HCID 7416 | — |
| 反応物 | 1-Bromo-2-nitrobenzene | HCID 11341 | — |
| 反応物 | 1-Ethyl-4-iodobenzene | HCID 141189 | — |
| 触媒 | Copper | HCID 23978 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 4-Ethyl-2-nitrobiphenyl | HCID 13320616 | — |
反応手順
Copper lining powder (75g) was added portionwise over 30 minutes to a stirred mixture of 1-ethyl-4-iodobenzene (34.8g, 0.15 mole) and 2-bromo-1-nitrobenzene (30.3g, 0.15 mole) in nitrobenzene (250 ml) at 160°. After stirring for a further 3 hours at 160° C the solution was cooled, diluted with methylene chloride and filtered. Methylene chloride was distilled, nitrobenzene was steam-distilled, and the product was isolated in ether, and distilled to give 4-ethyl-2-nitrobiphenyl, b.p. 120°-130° C/0.1mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04036989 |
|---|
| 出典データセット | uspto-grants-1977_07 |
|---|
| ORD ID | ord-e5c9f413df5340fcb9d5060d7b8670e4 |
|---|
| 出典メモ | uspto-grants-1977_07 |
|---|
