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Potassium Carbonate → 1-Adamantyl 3,4-dichlorophenylthiomethyl ketone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 3,4-Dichlorobenzenethiol | HCID 79964 | — |
| 反応物 | Bromomethyl tricyclo[3.3.1.13,7]dec-1-yl ketone | HCID 197820 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 1-Adamantyl 3,4-dichlorophenylthiomethyl ketone | HCID 21424044 | — |
反応手順
1-adamantyl bromomethyl ketone (1.3 g.), 1.1 g. of 3,4-dichlorothiophenol and 800 mg. of anhydrous potassium carbonate in 30 ml. of acetone are stirred at reflux overnight. The solvent is then removed and 60 ml. of water is added to the reaction mixture. The product is filtered off, washed with water and recrystallized from methanol to yield 1-adamantyl 3,4-dichlorophenylthiomethyl ketone, M.P. 105°-110.5° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04036975 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-5fa6384611b3406fa60c6e11270986ca |
| 出典メモ | uspto-grants-1977_07 |