化工社化工社 化学情報印刷レポート · 研究参考用
4-Hydroxybenzaldehyde → p-(2-(Dimethylamino)ethoxy)benzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxybenzaldehyde | HCID 126 | — |
| 反応物 | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | p-(2-(Dimethylamino)ethoxy)benzaldehyde | HCID 84823 | 46.6% |
反応手順
The reaction between 61.0 g (0.50 mole) of 4-hydroxybenzaldehyde, 24.0 g of 50% NaH, and 341 ml of 2.2 N (0.75 mole) 2-dimethylaminoethyl chloride in toluene in a procedure described for Example 2,part A, gives 45.0 g (46%) of colorless product, bp 140°-142°/2 mm. Lit. bp 185°-187°/15 mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04038274 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-a2ddb5f051504bd5afee04ff26e57a22 |
| 出典メモ | uspto-grants-1977_07 |