化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 5-Chloro-2-hydroxy-4-methylbenzenesulfonic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 4-Chloro-3-methylphenol | HCID 1732 | — |
| 反応物 | Phenol, 2,4-dichloro-3-methyl-6-nitro- | HCID 170222 | — |
| 生成物 | 5-Chloro-2-hydroxy-4-methylbenzenesulfonic acid | HCID 11042323 | — |
反応手順
According to the present invention there is provided a process for preparing 2-nitro-4,6-dichloro-5-methylphenol comprising sulphonation of 4-chloro-5-methyl-phenol with concentrated sulphuric acid at elevated temperature to form 2-sulpho-4-chloro-5-methylphenol, thereafter diluting the reaction mixture with water to a sulphuric acid content of 20 to 30%, chlorinating the resulting 2-sulpho-4-chloro-5-methylphenol with chlorine at elevated temperature and normal or elevated pressure to form 2-sulpho-4,6-dichloro-5-methylphenol and reacting the 2-sulpho-4,6-dichloro-5-methylphenol with nitric acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04038328 |
| 出典データセット | uspto-grants-1977_07 |
| ORD ID | ord-969d40e96a0947f5af9516ea01802910 |
| 出典メモ | uspto-grants-1977_07 |