Acetone → 2-(2-Methylsulfinylphenyl)oxazolo[4,5-b]pyridine

HRID 259546ノート

反応式

HRID 259546 の反応式
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[O:10][C:11]2[C:12]([N:17]=1)=[N:13][CH:14]=[CH:15][CH:16]=2.CC(C)=[O:20].I([O-])(=O)(=O)=O.[Na+]>O>[CH3:1][S:2]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[O:10][C:11]2[C:12]([N:17]=1)=[N:13][CH:14]=[CH:15][CH:16]=2)=[O:20]

参加物

5

反応物 3

HCID 180AcetoneHCID 124613832-(2-(Methylthio)phenyl)oxazolo[4,5-b]pyridineHCID 23667635Sodium periodate

生成物 1

HCID 227547742-(2-Methylsulfinylphenyl)oxazolo[4,5-b]pyridine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A solution of 0.5 g. of 2-(2-methylthiophenyl)oxazolo[4,5-b]pyridine in 50 ml. of acetone was treated with 3 g. of sodium metaperiodate. After stirring over the weekend at room temperature, the mixture was diluted with 30 ml. of water. The acetone was distilled out and the resulting precipitate was recrystallized to give 2-(2-methylsulfinylphenyl)oxazolo[4,5-b]pyridine, m.p. 153.5°-155.5° C.

後処理

  1. additionthe mixture was diluted with 30 ml
  2. distillationThe acetone was distilled out
  3. customthe resulting precipitate was recrystallized

出典と根拠

ORDレコード
ord-8b39d698b5f24b498428dfcb1cab2f3a
出典データセット
uspto-grants-1977_07
特許番号
US04038396

反応ノート

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