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Hydrochloric Acid → Spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Potassium Cyanide | HCID 9032 | — |
| 反応物 | Ammonium Carbonate | HCID 517111 | — |
| 反応物 | Cyclohexa(b)furan-4-one | HCID 21326097 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione | HCID 70547195 | — |
反応手順
A mixture of 2.7 g of cyclohexa(b)furan-4-one (Bull. Soc. Chim. Fr., 1967, 2796), 1.95 g of potassium cyanide and 9.6 g of powdered ammonium carbonate were heated with 40 ml of 95% aqueous ethanol at 110°-120° C. in a steel bomb for 16 hours. The reaction mixture was cooled, diluted with 200 ml of water, and acidified with 12 N hydrochloric acid. The precipitated product was isolated by filtration and recrystallized from ethanol to give 1.73 g of spiro[cyclohexa(b)furan-4,4'-imidazolidine]-2', 5'-dione, mp 245°-248° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147797 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-da22df0d8761434b9bbdfb30e3940d12 |
| 出典メモ | uspto-grants-1979_04 |