化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 3-(3-Chlorophenyl)prop-2-enoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Malonic Acid | HCID 867 | — |
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | 3-Chlorobenzaldehyde | HCID 11477 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3-(3-Chlorophenyl)prop-2-enoic acid | HCID 74631 | — |
反応手順
The starting material is prepared as follows: The mixture of 50 g of 3-chlorobenzaldehyde, 41 g of malonic acid and 36 ml of pyridine is heated on the steam bath for 3 hours. The residue is dissolved in 200 ml of water, the solution acidified with hydrochloric acid, filtered, and the residue recrystallized from aqueous ethanol, to yield the 3-chlorocinnamic acid melting at 150°-152°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147786 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-bdef277686ca4cf78ffde5dfc821e56d |
| 出典メモ | uspto-grants-1979_04 |