Phosphinic Acid → 1-Benzhydrylamino-2-methylpropanephosphonous acid

HRID 25973

反応式

HRID 25973 の反応式
[PH2:1]([OH:3])=[O:2].[CH:4](=[N:8][CH:9]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH:5]([CH3:7])[CH3:6]>C(O)C>[CH:9]([NH:8][CH:4]([P:1]([OH:3])[OH:2])[CH:5]([CH3:7])[CH3:6])([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

参加物

4

反応物 2

HCID 4124402Phosphinic AcidHCID 10657527Isobutylidenebenzhydrylamine

生成物 1

HCID 213258821-Benzhydrylamino-2-methylpropanephosphonous acid

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

Hypophosphorous acid (100%, 15.8 parts) dissolved in absolute ethanol was added to a stirred solution of 41.3 parts isobutylidenebenzhydrylamine in absolute ethanol. An exothermic reaction occurred. After standing one hour the reaction was filtered and the white solid dried in vacuo. There was obtained DL-1-benzhydrylamino-2-methylpropanephosphonous acid, melting point 191° (dec.).

後処理

  1. customAn exothermic reaction
  2. filtrationthe reaction was filtered
  3. customthe white solid dried in vacuo

出典と根拠

ORDレコード
ord-bee6e3df24624b6d98464e0a489e9362
出典データセット
uspto-grants-1979_04
特許番号
US04147780

関連ノート

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