2-[5-(Ethanesulfonyl)-2-methoxyphenyl]-1H-pyrrole → HCID 22403071、化合物
反応式
[Br:1][C:2]1[C:3]([O:18][CH3:19])=[C:4]([C:13]2[NH:14][CH:15]=[CH:16][CH:17]=2)[CH:5]=[C:6]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])[CH:7]=1.C(S(C1[CH:26]=[CH:27][C:28](OC)=[C:29]([C:31]2[NH:32][CH:33]=CC=2)C=1)(=O)=O)C>>[Br:1][C:2]1[C:3]([O:18][CH3:19])=[C:4]([C:13]2[NH:14][C:15]([CH2:33][N:32]3[CH2:31][CH2:29][CH2:28][CH2:27][CH2:26]3)=[CH:16][CH:17]=2)[CH:5]=[C:6]([S:8]([CH2:11][CH3:12])(=[O:10])=[O:9])[CH:7]=1参加物
3
実験手順
This compound was prepared by a method analogous to that used to prepare example 2, but using 2-(3-bromo-5ethylsulphonyl-2-methoxy-phenyl)-1H-pyrrole (prepared according to the method of Kruse et al., [Heterocycles, 26,3141, 1987] from the corresponding acid chloride) in place of 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole. NMR δ(CDCl3) 1.30-1.70 (9H, m), 2.40 (4H, m), 3.15 (2H, q, J=7 Hz), 3.50 (2H, s), 3.80 (3H, s), 6.10 (1H, t, J=2 Hz), 6.60 (1H, t, J=2 Hz), 7.80 (1H, d, J=1 Hz), 8.00 (1H, d, J=1 Hz), 9.9 (1H, s).
後処理
- customThis compound was prepared by a method analogous to
- customto prepare example 2
- customprepared