Water → 1-Amino-p-methoxyphenylmethanephosphonous acid

HRID 25983

反応式

HRID 25983 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]=O)=[CH:7][CH:8]=1.[PH2:11]([O-:13])=[O:12].[NH4+:14].O>C1(C)C(C)=CC=CC=1>[NH2:14][C:6]1([CH2:9][P:11]([OH:13])[OH:12])[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH2:7]1

参加物

5

反応物 3

HCID 962WaterHCID 312444-MethoxybenzaldehydeHCID 178418291HCID 178418291、化合物

生成物 1

HCID 867364411-Amino-p-methoxyphenylmethanephosphonous acid

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒2 回

実験手順

A mixture of 13.6 parts anisaldehyde and 8.3 parts ammonium hypophosphite in 100 parts xylene was refluxed with water separation. The xylene was cooled, decanted and the residue boiled with ethanol to give a white solid. Filtration gave DL-1-amino-p-methoxyphenylmethanephosphonous acid, melting point 239°-241° (dec.).

後処理

  1. customdecanted
  2. customto give a white solid
  3. filtrationFiltration

出典と根拠

ORDレコード
ord-24e4c99b0b07489a91a8b31e14f959c8
出典データセット
uspto-grants-1979_04
特許番号
US04147780

関連ノート

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