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4-Methoxyphenylacetaldehyde → 1-Benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methoxyphenylacetaldehyde | HCID 79782 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | HCID 178527021 | HCID 178527021 | — |
| 生成物 | 1-Benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid | HCID 21325881 | — |
反応手順
10 parts of freshly distilled p-methoxyphenylacetaldehyde in 20 parts of sodium-dried dioxan was added to a suspension of 17 parts of benzhydrylammonium hypophosphite in 100 parts of sodium-dried dioxan under reflux and under nitrogen as in Example 17 above. 70 Parts dioxan/water was removed. 125 Parts of alcohol was added and DL-1-benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid, melting point 199°-202°, was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04147780 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-dd34e67a365840f7bd89be9836dcf4be |
| 出典メモ | uspto-grants-1979_04 |