化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → 2-Amino-5-fluorobenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | 2-Bromo-5-fluorobenzoic acid | HCID 2778181 | — |
| 反応物 | Sodium | HCID 5360545 | — |
| 反応物 | Potassium | HCID 5462222 | — |
| 溶媒 | Potassium Hydroxide | HCID 14797 | — |
| 生成物 | 2-Amino-5-fluorobenzoic acid | HCID 101412 | — |
反応手順
If the sodium salt solution of 5-fluoro-2-bromobenzoic acid is replaced by aliquot parts of the potassium or ammonium salt solution, prepared by dissolving 219 parts of 5-fluoro-2-bromobenzoic acid in 256.1 parts of 21.9% strength aqueous potassium hydroxide or, respectively, 217 parts of 7.9% aqueous ammonia solution and used as the metering medium in a procedure otherwise identical to that indicated, then 5-fluoroanthranilic acid is obtained in identical yield and quality.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05523472 |
| 出典データセット | uspto-grants-1996_06 |
| ORD ID | ord-4f2f20decea5457bb0487fd375f40d1a |
| 出典メモ | uspto-grants-1996_06 |