Trioctylamine → Methyl 2,3,4,5-tetrafluorobenzoate

HRID 259956

反応式

HRID 259956 の反応式
[CH3:1][O:2][C:3](=[O:17])[C:4]1[C:5](=[C:9]([F:16])[C:10]([F:15])=[C:11]([F:14])[C:12]=1[F:13])C(O)=O.C(N(CCCCCCCC)CCCCCCCC)CCCCCCC>>[CH3:1][O:2][C:3](=[O:17])[C:4]1[CH:5]=[C:9]([F:16])[C:10]([F:15])=[C:11]([F:14])[C:12]=1[F:13]

参加物

3

反応物 2

HCID 14227TrioctylamineHCID 108579443,4,5,6-Tetrafluorophthalic acid-monomethyl ester

生成物 1

HCID 600996Methyl 2,3,4,5-tetrafluorobenzoate収率 86.4%

反応条件

温度
140 °C

実験手順

Into a 100 ml three necked flask, 20 g (0.079 mol) of the 3,4,5,6-tetrafluorophthalic acid-monomethyl ester prepared in Example 14, and 2.8 g (0.0079 mol) of tri-n-octylamine were charged, and the mixture was heated and stirred at 140° C. for 24 hours. After completion of the reaction, the reaction mixture was separated by distillation to obtain 14.2 g of 2,3,4,5tetrafluorobenzoic acid methyl ester. The yield was 86.3%.

後処理

  1. temperaturethe mixture was heated
  2. customAfter completion of the reaction
  3. customthe reaction mixture was separated by distillation

出典と根拠

ORDレコード
ord-e72bc0d2a4474c13ae3b233e513741cc
出典データセット
uspto-grants-1996_06
特許番号
US05523476

関連ノート

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