Toluene → HCID 11030613、化合物

HRID 259985ノート

反応式

HRID 259985 の反応式
[Cl:1][C:2]([CH2:4]Cl)=[CH2:3].[CH2:6]([OH:13])[CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C1(C)C=CC=CC=1>[Zn].O>[Cl:1][C:2](=[CH2:3])[CH2:4][CH:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[OH:13]

参加物

6

反応物 3

HCID 1140TolueneHCID 65652,3-DichloropropeneHCID 8129Heptanol

生成物 1

HCID 11030613HCID 11030613、化合物収率 94.1%

試薬・触媒・溶媒 2

HCID 23994Zinc触媒2 回HCID 962Water溶媒

実験手順

58.30 Grams of 2,3-dichloro-1-propene were added dropwise to a mixture of 30.00 g of heptanol, 90 g of toluene, 120 g of water and 34.35 g of zinc powder at 45° C., and then the resultant mixture was allowed to react at the same temperature for 10 hours. After the reaction finished, zinc-derived insolubles were filtered off, and the resultant filtrate was subjected to separation. The organic phase was washed with a 7% sodium carbonate aqueous solution and then dried over sodium sulfate. The desiccant was filtered off, and then the toluene was distilled off under reduced pressure to give 47.14 g of 2-chloroallyl-n-hexylcarbinol. The results were as follows.

後処理

  1. customto react at the same temperature for 10 hours
  2. filtrationwere filtered off
  3. customthe resultant filtrate was subjected to separation
  4. washThe organic phase was washed with a 7% sodium carbonate aqueous solution
  5. dry with materialdried over sodium sulfate
  6. filtrationThe desiccant was filtered off
  7. distillationthe toluene was distilled off under reduced pressure

出典と根拠

ORDレコード
ord-061686e02a614a8e9eb59b3351843f22
出典データセット
uspto-grants-1996_06
特許番号
US05523495

反応ノート

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